I have a theory for this, the first half being for her Pinkie Sense, and the other for her hyperactivity.
Some people have hyperactive senses, meaning that one of their senses is working overtime, so they can see, hear, taste, smell, or feel more. I feel that Pinkie is able to sense certain things because her senses are on overdrive, allowing her to feel footsteps leading to a door (touch), sense an alligator in a tub or an object dropping (hearing), or other events in the immediate future. When Pinkie Pie senses something, her body sends a "code" in the form of various bodily movement, such as eye flutter, twitchy tail, or knee twitch, and she decodes this as the next event.
When it comes to her hyperactivity, my best theory is that Pinkie Pie has some form of ADHD, which makes the body produce a large amount of adrenaline. This allows her to be able to run fast for large distances. She may also have a larger amount of magic in her than most earth ponies, which makes her stronger and faster than others. She may also have some pure magic essence inside of her, which allows her to create "portals" in space and defy gravity. The magic most likely came from the Sonic Rainboom, which made Rainbow Dash faster, gave Twilight a boost in magic, gave Fluttershy the ability to communicate with animals, etc. This could be the reason why Pinkie is able to experience a lot more emotion than the other Pie sisters. It could also explain how pony Pinkie and human Pinkie are able to know what happens on the other side of the mirror in the Equestria Girls series, because they have already made contact with each other through portals.
Hope this answered your question.